This course focuses on the evaluation and treatment of the spine, specifically from the upper cervical region through the thoracic, lumbar spine, and pelvis—areas commonly addressed in physical therapy. The most effective treatment approach for these regions integrates the American College of Physicians’ categorization of pathological, neurological, and nonspecific conditions. Advancements in improving the classification of nonspecific conditions into distinct syndromes have contributed to better advocacy and improved patient outcomes. Participants will learn effective and timely examination techniques for each region and some of the most evidence-based manual therapy treatment approaches. The course also covers exercise progressions, ranging from core stability to more dynamic, global movements. An eclectic, evidence-based approach is emphasized, incorporating current concepts from the orthopedic section of the American Physical Therapist Association’s curriculum.